Frequently Asked Questions (Patients)- Purchase and Reservation process - step by step ...
Purchase and Reservation step by step:
See eventually the video how to buy step by step.
Click the › to start the film. Please observe that you may need a Microsoft Silverlight program to runn the video. The program can be downloaded if you accept the installation popup.
- As long as you have not finished item 10, the order has not been completed. You can therefore do excersise as much as you want without consequences.
- Please observe that orders not proceede according to item 10 will be deleted 20 minuttes.
1. Click the menu or the bottom Donor Search. You can now browse through the donor list. You can search for specific characteristics or qualities. You can sort the donors by clicking the top bar in each column - for instance Race or Hair colour.
2. Donors with Extended Profile: click the icon in order to see the extended profile, staff impression and baby-photos of the donor. In order to open these files (pdf) you need Adope Acrobat Reader.
3. If you wish to se which qualities (IUI/ICI or MOT) we have in stock from a donor - and the prices, you can click the line for the specific donor (mouse over - line turn into grey).
4. Write the wanted quantity of units (straws) on each line in the squares Delivery and/or Reservation - click the basked. You can order delivery and reservation in the same order. The sum of your purchase/reservation is shown in the frame in the top of the screen.
5. If you want to check if a donor has reached the pregnancy quota in your country you can see this in the lower left corner of the screen under "Check pregnancy quota?". Write your own country in Patient country and your clinic's country in Clinic country. If the quota is reached it will immediately be shown.
6. Check the details in your order. You can cancel any line in case of mistakes and you can go back by using the blue/white arrows.
7. Choose a shipping method (Delivery) and/or a storage period (Reservation). Click the arrow to the right in order to go to next page.
8. New Clients: Write a username and a password of your own choice. You can use any alpha-numeric sign between 8-15 characters. Write your e-mail address. Click the square "I accept Terms of Agreement" (mandatory in order to continue). Click Create Client.
Existing Clients: Write your username and password and clic Login. If you have forgotten your username and password, please write your email and click "Send Password". An email will automatically be sent to you with your username and your password.
9. Fill in your name and address under Invoice address - i.e. you as the purchaser. Fill in the clinics name and address where the semen shall be delivered to. If delivery should go to the Invoice address or a third address or if it is picked up, click the square "Same as Invoice address".
Observe that the Delivery Authorisation is signed by an authorised person and sent to Cryos before delivery can take place! Click [Submit order].
10. Select your payment method (Dankort, Visa, MasterCard or JCB) and fill in the payment site with your card number, expiry date and control numbers (3 numbers on the back side of your card).
When the order has been sent to us a confirmation of the receipt will be sent by email. Within 2 working days we will send you an order confirmation.
If you have any questions please don't hesitate to contact us. Either by email, phone, letter or fax.
- Which information about the donor is available?
We have two types of donors: Basic and Extende profile.
In both groups are Anonymous and Non-anonymous donors. Donors with Extended profile:
Registered by a fictitious name (Eric, Bob, Bond, Cliff, etc.).
Extended Profiles with comprehensive information about donors background, education, family relations, a hand written message, etc.
Normally there is a Staff impression - i.e. a short, subjective description from our staff.
There are often photos from the donor' childhood.
We do not make any control of the information given in the Extended profiles except those given in Basic profile. These information are published as we receive them from the donor.
Donors with Basic profile:
Registrered with a number (3456, 8756, 11250, etc.).
Only registered by few characteristics (race, ethnicity, eye color, hair colour, heigh, weight, blood type and in most cases education/occupation). No staff impression and no photos. We do not make any control of the education/occupation. Whether to choose a donor with Basic or Extended profile is a very difficult decision.
If many data about the donor is important to you, you should choose a donor with Extended profile. Single women and lesbians who often have an explicit needs to keep information for the children, may have a preference for Extended profile donors. However, before you choose please make sure that the clinic accepts treatment with Extended profile donors. Some clinics only treat with Basic profile donors.
If you want to know as little as possible about the donor, you should choose a Basic profile donor. In many cases heterosexual couples prefer a Basic profile donor in order to protect their own interests as a family. Anonymous donors:
Anonymous donor's identity is kept secret forever. Non-anonymous donors:
Non-anonymous donor's identity can be disclosed to offspring when they reach 18 years of age and if they apply for it. Whether to choose an Anonymous or a Non-anonymous donor is also a difficult decision?
In some countries it is illegal to use non-anonymous donors and in other countries it is illegal to use anonymous donors. The issue has been discussed international for many decades and there is no single solution. Only the parents can choose what they think is best for them. It seems that singles and lesbian couples may prefer Non-anonymous donors and heterosexual couples seems to prefer Anonymous donors. Both for the same reason as they select Basic and Extended profile donors. But it is not always so. Singles may for instance prefer an Anonymous donor because they plan to find a spouse later who can then easier be a father and adopt the child. Heterosexual couples sometimes prefer a Non-anonymous donor because they plan to tell the child about its origin.
If you live in a country where you cannot be treated with the type of donor you prefer, you must find a fertility clinic in another country. Use search engine as Google, Yahoo, etc. or you can try World In Vitro Fertilisaton Unit.
Alternatively you can try to get a Delivery Authorisation - maybe even from authorised persons/clinics outside your country? - How much sperm should I order?
ICI-unwashed:
For vaginal/cervical insemination
We recommend to use 2 x MOT20 straws or higher qualities per treatment.
If ICI-unwashed is sold out IUI-ready can be used for vaginal insimination, even this is wast of quality. Because of the concentration at least 2 x IUI-MOT20 straws or higher quality should be used per insemination.
For Interuterine Insemination
If the sperm is prepared by swim-up method, we recommend to use 2 x MOT20 straws or higher qualities per treatment.
If the sperm is prepared by gradient-centrifugation method all ICI-unwashed qualities can be used because the concentration is a result of concentration/dilution after the preparation. After preparation there should be a minimum of 2 million motile spermatozoa per ml. for IUI.
We recommend to use for instance 8 x MOT5, 4 x MOT10 or 2 x MOT20 straws (or higher) per treatment. The concentration after preparation will in principle be the same.
IUI-ready:
For interuterine insemination.
We recommend to use 1 or 2 x IUI-MOT5 straws or 1 x IUI-MOT10 straw per treatment. IUI-MOT20 or higher quality can be used, but this this is in principle to "take a musket to kill a butterfly".
Intra-uterine treatment may only be performed by authorised persons!
Shipping costs:
In order to reduce the shipping costs we recommend to order sufficient numbers of straws delivered for 2-3 cycle treatments, but on the other hand you can also "risk" to be pregnant before all material is used. The question is what to do with the remaining straws at the clinic if you get pregnant? Cryos do not take straws back for security reasons.
Ask your clinic or contact one of our sales staff with regard to quantity and quality. - Can I make a reservation?
When you have found your donor, you should consider to reserve sufficient quantity of straws not just for one but maybe also for more pregnancies? Otherwise you will risk that donor is sold out.
Averagely it takes 5-6 cycle treatments to achieve pregnancy. Clinics report an average pregnancy rate between 10-40% per cycle treatment. It differ much from clinic to clinic and from person to person depending on the patient's fertility/health (age, diagnosis for infertility), clinic's experience, hormone stimulation, timing of the treatment, sperm preparation method, the quality of sperm, insemination method, etc. The pregnancy rate is higher in the beginning (because the most fertile get pregnant first) and decrease with more treatments. Accumulated 50-60% in an unselected group of patients will conceive after six month attempts, and about 80% after 12 attempts. ICI-unwashed:
We recommend to reserve 48 x MOT5, 24 x MOT10, 12 x MOT20 or 6 x MOT40 (or higher) straws per pregnancy.
Any proposional distribution can also be made. For instance 14 x MOT5, 3 x MOT10 and 7 x MOT20.
If you for want for instance 3 children you should reserve 3 times as much.
IUI-ready:
We recommend to reseve 24 x IUI-MOT5, 12 x IUI-MOT10 or 6 x IUI-MOT20 (or higher) straws per pregnancy.
Any proposional distribution can also be made. For instance 6 x IUI-MOT5, 7 x IUI-MOT10 and 1 x IUI-MOT20.
If you want for instance 3 children yous should reserve 3 times as much.
Remember that above recommendations are based on averagely consumption.
Reasons to reserve less: If you easy become pregnant. If you are treated with IVF. If you are yonger than 35 years of age. If you have decided a lower maximum number of treatments - for instance 3 cycle treaments. It can be very expensive or very traumatic to continue treatment year after year.
Reasons so reserve more:
If you have difficulties to become pregnant. If you are treated vaginal/cervical. If you are older than 35 years of age. If you want a higher or unknown maximum number of treatments. Just want to be moe safe. As more material as safety.
Better to reserve more than needed. 90% of the straw-price for straws still in Cryos' position is paid back by release of the reservation. Read more about Reservation here ...
If you change donor we offer to replace any reserved straws free of charge.
If you have questions you should ask your clinic or contact one of our sales staff.
- What is a Standard?
Cryos Deliver donor semen to many countries and as different countries has different approval procedures for donors and for donor semen Cryos operate with different Standards for release. I.e. that donors can be selected and tested according to one or several of these Standards. Read more about Standard here ... Read more about Screening here here ... - Where can I find a fertility clinic?
- What is Intra Uterine Insemination (IUI)?
The insemination of spermatozoa directly into the uterine cavity is called IUI. Scientific studies have shown a three to four times higher pregnancy rate through IUI than through vaginal or cervical insemination. However, before IUI can be carried out, the semen must be preparated through swim-up or by density gradient centrifugation in order to remove prostaglandins (from the prostata) and bacteria in the semen. If this is not done, the patient may react negatively or get severe cramps. - What does MOT mean?
MOT means motility (ability to move or swim) and 20 means 20 million pr. ml. The term states that there are a minimum of 20 million motile spermatozoa pr. ml in the sample after thawing according to the WHO-standard (grade a and b).
We operate with following qualities:
MOT5, MOT10, MOT20, MOT30 MOT40 and MOT50+
IUI-MOT5, IUI-MOT10 and IUI-MOT20+ (IUI stands for Intra Uterine Insemination directly). - What is Vaginal or Cervical Insemination?
The insemination of sperm in vagina or the cervical channel can be done with raw or unwashed semen. Intra uterine insemination (IUI) normally results in 3-4 times higher pregnancy rate per cyclus than vaginal or cervical insemination. - Do you deliver ICI-unwashed or IUI-ready?
We deliver both ICI-unwashed and IUI-ready. Some call it raw semen or prepared semen or just washed or unwashed. IUI means "Intra Uterine Insemination" or "insemination directly in the uterus cavity". ICI means "insemination in the cervical channel". Even though the expression is not totally correct, it has gained acceptance as such. The sperm is just raw or unwashed.
Raw semen (or unwashed) can only be used for vaginal or cervical insemination as it contain prostaglandins and bacteria which may not be inseminated into the uterus. IUI-ready semen has been treated by a so called gradient centrifugation method where prostaglandins and bacteria has been removed from the plasma. IUI-ready semen can be inseminated directly into the uterus or used for IVF.
Raw semen can also be used for IUI or IVF, but not until aftre thawing and following a preparation - either by use of swim-up (not recommended for frozen-thawed samles) or by gradient centrifugation.
Both raw semen and IUI-ready is delivered in different qualities from MOT5 to MOT50+ (raw semen) and MOT5 to MOT20+ (IUI). - What is a straw?
Semen is delivered in clear 0.4 or 0.5 ml CBS high security straw. Each straw is marked with the donor number or fictitious name and the ejaculate number (for example "7890-12" or "CLIFF-25"). CBS® (CryoBioSystem) High Secutity Straws are specifically manufactured for safe cryo storage of biological products in liquid nitrogen. Applications include storage of serum, plasma, buffy-coat and other blood fractions, cell suspension, bacterial or viral strains, gametes and embryos. Directly after filling, both extremities of the CBS™ High Security straw are thermally sealed with one of our specific machines. This makes the straw absolutely leakproof, preventing contamination of the sample and its environment.
Manufactured from biocompatible materials, they are used in medically assisted procreation techniques and particularly for sperm preservation. The CBS™ straw is a clear, flexible tube made of ionomeric resin.
Length: 133 mm (130 mm after sealing).
Sterilized by irradiation.
The straw is 510 (k) FDA-cleared and CE-marked as a medical device for storage of human gametes and embryos.
See also RBM Online - Vol 9. No 2. 2004 134-151. Article 1256. The article has an in depth comparison of vials and CBS straws. 
- Are bloodtype important for my choice of donor?
The question can be interesing in 2 cases:
1) If the womans blood type are Rhesus negative (expressed Rh-) and if donor is Rh+. In these cases there is 50% risk that the child will get the bood type Rh+. In that case the mother can create antibodies agains the child. This is normally not at problem in the first pregnancy, but at following pregnancies the child's condition must be followed carefully.
2) Hvis you don't want to inform the child about its createion and if the social father's blood type are different than the possible combinations according to the donors blood type, in rare cases, if the child later in life will be informed about its blood type, it will be clear, that the social father cannot be the genetic father. If you are planning to tell the child about its creation, it has no relevance.
It is very seldom that we experience that the blood type is important in the choice of donor. If you choose donor according to blood type, you must be avare, that this can limit the selection of donors significantly. - How many children per donor?
It is Cryos International's policy to follow any national limitation or national quotas*. Pregnancy quotas are made in order to limit the risk of inbreeding. However, due to strict regulation in many countries low supply of donor semen is a consequence, which lead many patients to cross boarders ("fertility tourism") in order to receive treatment. In order to track these patients and pregnancies Cryos operate with a wordwide quota system** You can always check if a donor has reached the national or the worldwide quota under Donor Search when you click on a donor - Donor Details (Check pregnancy quota ?)
*) The "national quota" is the maximum number of pregnancies per donor based on any kind of regulation in the form of laws, circular letters, or collective agreements from organizations in the country in question (if such limitations are known to Cryos). Siblings and abortions are not included.
**) "Cryos' “worldwide quota" is a general limit of 1 pregnancy per 200,000 citizens in the patient's country. Siblings and abortions are not included. This quota only takes into consideration the nationality of the patient not the country in which the patient is treated.
Example:
If a Finnish woman is treated in Finland, her pregnancy will count in the national quota which is 5 pregnancies (abortions and siblings not included) per donor. Her pregnancy will also count in the worldwide quota. If she is treated in the UK her pregnancy will neither have an influence on the Finnish nor the UK national quotas. However, it will influence the worldwide quota (1 pregnancy per 200,000 citizens in the patient’s country) which in this case is 26 pregnancies (Finnish citizens 5,223,442 : 200,000 = 26 pregnancies). - When can I expect delivery?
Orders:
Smaller or easy orders received before 11.00am can be shipped same day.
Smaller or easy orders can - against en express fee - and if received before 2.00pm be shipped same day.
Larger or more complicated orders cannot be shipped same day we receive the order.
Delivery time:
Mumbai: Normally next weekday.
India: Normally 1-5 week days from shipment.
Rest of the world: Normally 1-2 weeks depending on destination. For some distinations custom clearance procedure can prolonge the delivery time even more.
Cryos refrain from all kind of responsibility in case of delay. Delivery will some times take longer than expected and ovulation time can be difficult to predict. Therefore it is recommended to order in good time before planned use. If you have a local nitrogen storage tank we recommend dry-ice shipments, but only for shipments Monday through Thursday. Dry-ice (5 kilos) thaws after about 24 hours. 
In case where you do not have a nitrogen storage tank or shipments Thursday through Friday we strongly recommend shipments in nitrogen tanks as they last longer. Nitrogen tanks thaw after 1 week (small tanks) or 2 weeks (large tanks). . - Should I order in good time before ovulaton?
Do you recommend to order the semen some days before ovulation or doesn't it matter because the semen can stay frozen?
If the semen is delivered to a clinic, they wil normally have a nitrogen storage tank, to where the sraws can be transfered upon arrival. But if the semen is to be delivered at home according to a Delivery Authorisation, it is best to order some days before shipping shall take place, because we need time for the handling, packing, security control, etc. As it is difficult to say exactly when ovulation take place, and as dry-ice only last 24 hours before it is thawed. This is also why we only ship dry-ice Monday through Wednesday in order not to come into the weekend before delivery take place. If you want to be sure that the semen arrive in good time without thawing before ovulation, you should order on a nitrogen tank - even it is more expensive. A nitrogen tank can stay frozen for 1-2 weeks depending on type of tank. - What are the sales- and delivery terms?
- What documentation will follow the shipment?
Invoice, Packing List, Donor Characteristic & Quarantine Release form (see example, click here ...).
The DC&CR-form shows what Standards the donor and ejaculates is released to. It also indicate if the the donor has reached any pregnancy quotations.
Instructions to the clinic how to handle the semen is written in the Packing List. - Which currencies do you accept?
All online credit card payments must be in Indian Rupies (INR).
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